Industry · Biomedical

Biomedical systems

A wearable biosensor has to be most accurate exactly where it is hardest: at low signal, under rapid change, inside a shrinking power and size budget. Agentriq treats that trade-off as an engineering problem you can simulate, learn from, and close a loop on.

01The problem

Continuous glucose monitors from makers such as Abbott and Dexcom are least accurate in the low-glucose, rapid-change regime where a wrong reading is most dangerous. Published point-accuracy studies show mean absolute relative difference roughly doubling below 70 mg/dL, and worse still when glucose moves faster than 3 mg/dL per minute, while power, latency and footprint all have to keep shrinking. Accuracy at the edge of the signal, not average accuracy, is the figure that decides safety.

hypoglycemia (< 70 mg/dL)4070130190250reads high, misses the lowGlucose (mg/dL)Timereferencesensor estimateMARD by band>18070-180<70glucose band
Where accuracy fails first. For CGMs from makers such as Abbott and Dexcom, accuracy is worst exactly in the low-glucose, rapid-change band. This shows the field-wide pattern, not any single device.

02How we solve it

Simulate the device, learn the signal.

Agentriq couples physics-based device simulation with deep learning on physiological signals, then optimizes both against the low-signal regime that actually fails.

MultiphysicsCOMSOL / FluentSignal modelPyTorch · PhysioNetMulti-objectivejoint optimizationEdge / FPGAVitis AIaccuracypowerlatencyfootprintagent loop: re-optimize against the low-signal regime
From physics to the edge. One pipeline: simulate the sensor, learn the physiological signal, then optimize and quantize it down onto the wearable.

Simulation-driven biosensor and microfluidic design

Multiphysics models in COMSOL and ANSYS Fluent couple diffusion, electrochemistry and flow to predict sensor response and refine electrode geometry before any device is fabricated.

Deep learning for physiological signals

Convolutional and recurrent networks trained on MIT-BIH and PhysioNet records reach roughly 99 percent arrhythmia classification accuracy on ECG, with matching pipelines for EEG and PPG.

Multi-objective device optimization

Accuracy, power, latency and footprint are optimized jointly, so gains in the low-glucose regime are not silently paid for in battery life or size.

Edge and FPGA real-time inference

Quantized, pruned models are mapped to FPGAs with Xilinx Vitis AI for sub-watt, millisecond-scale inference running on the wearable itself.

03What it produces

Sub-watt inference at full accuracy.

ACCURACY holds near 99% across both implementationsPower (W)~4.5CPU/GPU0.33FPGAPer-beat latency (ms)~40CPU/GPU11.5FPGAorder-of-magnitude lower power and latency on the wearable itself
Sub-watt, millisecond, near-perfect. Published edge deployments show a compact FPGA holding near 99 percent ECG arrhythmia accuracy at sub-watt power and millisecond latency, shown as an example of the field's achievable envelope.

In published edge deployments, a compact FPGA runs per-beat ECG arrhythmia inference in roughly 11 milliseconds at about 0.33 watts while holding near 99 percent accuracy, the kind of accuracy, power and latency budget a wearable can actually meet.

04The agentic loop

Every design run verified and judged.

Agentriq runs the whole pipeline as a closed agent loop: it proposes a design, simulates and scores it, verifies the result, finds the root cause when a target is missed, and writes the decision back.

EVERY RESULT becomes a decisionDesigndevice + modelVerifyre-check, convergeRoot-cause+ Agentic RAGJudgeAcceptIterateEscalateoutcome + evidence written back to structured memory
From work to a verified decision. The agent proposes, simulates, verifies, finds root cause, judges, and writes the outcome back before the next iteration begins.
  1. 01Propose a device geometry, physiological-signal model and edge configuration from the current targets and constraints.
  2. 02Run the multiphysics simulation and signal-model training, then score accuracy, power, latency and footprint against the low-signal regime.
  3. 03Verify the result against held-out data and physical sanity checks before it is allowed to count.
  4. 04On a missed target, trace the root cause with Agentic RAG over prior runs, datasheets and literature, then a judge weighs the trade-off and decides advance, re-optimize or reject.
  5. 05Write the verified outcome, rationale and metrics back to the design record so the next iteration starts from ground truth.

05Tooling

Simulation, solvers & frameworks.

  • COMSOL Multiphysics
  • ANSYS Fluent
  • MATLAB / Simulink
  • PyTorch
  • TensorFlow
  • scikit-learn
  • MIT-BIH / PhysioNet
  • Xilinx Vivado / Vitis AI

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